Product Datasheet  
Nicotinic Acetylcholine Receptor alpha 4 Antibody  
Catalog Number: 35433  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P43681;
    NCBI Gene#:1137
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 53 and 280 of Nicotinic Acetylcholine Receptor alpha 4.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • BFNC antibody; EBN antibody; EBN1 antibody; FLJ95812 antibody; NACHR antibody; NACHRA4 antibody; NACRA4 antibody; CHRNA4 antibody; neuronal nicotinic acetylcholine receptor alpha-4 subunit antibody; "cholinergic receptor; nicotinic; alpha polypeptide 4 an
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total Nicotinic Acetylcholine Receptor alpha 4 protein.
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. [provided by RefSeq]



 
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