Product Datasheet  
FLIP Antibody  
Catalog Number: 35423  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O15519;
    NCBI Gene#:8837
  • Form of Antibody：  
  • Rabbit IgG in 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region within amino acids 418 and 480 of FLIP.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • CASH antibody; CASP8AP1 antibody; CLARP antibody; Casper antibody; FLAME antibody; FLAME-1 antibody; FLAME1 antibody; FLIP antibody; I-FLICE antibody; MRIT antibody; c-FLIP antibody; c-FLIPL antibody; c-FLIPR antibody; c-FLIPS antibody; CFLAR antibody; ca
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total FLIP protein.
  • Applications：  
  • WB
  • Background：  
  • Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.



 
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