Product Datasheet  
USP14 Antibody  
Catalog Number: 35419  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P54578;
    NCBI Gene#:9097
  • Form of Antibody:  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region within amino acids 1 and 44 of USP14.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500-1:3000
  • other_names:  
  • TGT antibody; USP14 antibody; ubiquitin-specific-processing protease 14 antibody; deubiquitinating enzyme 14 antibody; ubiquitin specific protease 14 (tRNA-guanine transglycosylase) antibody; ubiquitin thioesterase 14 antibody; ubiquitin-specific processi
  • Purification:  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity:  
  • The antibody detects endogenous levels of total USP14 protein.
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]



 
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