Product Datasheet
USP14 Antibody
Catalog Number: 35419
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P54578;
NCBI Gene#:9097
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Synthetic peptide corresponding to a region within amino acids 1 and 44 of USP14.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- TGT antibody; USP14 antibody; ubiquitin-specific-processing protease 14 antibody; deubiquitinating enzyme 14 antibody; ubiquitin specific protease 14 (tRNA-guanine transglycosylase) antibody; ubiquitin thioesterase 14 antibody; ubiquitin-specific processi
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total USP14 protein.
- Background:
- This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
© Signalway Biotechnology All Rights Reserved.