Product Datasheet
FBXW11 Antibody
Catalog Number: 35405
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UKB1;
NCBI Gene#:23291
- Form of Antibody:
- Rabbit IgG in 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 32 and 321 of FBXW11.
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
IHC 1:50 - 1:200
- other_names:
- BTRC2 antibody; BTRCP2 antibody; FBW1B antibody; FBXW1B antibody; Fbw11 antibody; Hos antibody; KIAA0696 antibody; FBXW11 antibody; F-box and WD-40 domain protein 1B antibody; F-box and WD repeats protein beta-TrCP2 antibody; F-box protein Fbw1b antibody;
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total FBXW11 protein.
- Background:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq]
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