Product Datasheet  
FBXW11 Antibody  
Catalog Number: 35405  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9UKB1;
    NCBI Gene#:23291
  • Form of Antibody:  
  • Rabbit IgG in 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fragment corresponding to a region within amino acids 32 and 321 of FBXW11.
  • reactivity:  
  • Human,Mouse,Rat
  • appl_detail:  
  • WB 1:500 - 1:2000
    IHC 1:50 - 1:200
  • other_names:  
  • BTRC2 antibody; BTRCP2 antibody; FBW1B antibody; FBXW1B antibody; Fbw11 antibody; Hos antibody; KIAA0696 antibody; FBXW11 antibody; F-box and WD-40 domain protein 1B antibody; F-box and WD repeats protein beta-TrCP2 antibody; F-box protein Fbw1b antibody;
  • Purification:  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity:  
  • The antibody detects endogenous levels of total FBXW11 protein.
  • Applications:  
  • WB,IHC
  • Background:  
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq]



 
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