Product Datasheet
BLMH Antibody
Catalog Number: 35402
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13867;
NCBI Gene#:642
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 60 and 268 of BLMH.
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- BH antibody; BMH antibody; BLMH antibody; bleomycin hydrolase antibody; BLM hydrolase antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total BLMH protein.
- Background:
- Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq]
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