Product Datasheet  
FGR Antibody  
Catalog Number: 35401  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P09769;
    NCBI Gene#:2268
  • Form of Antibody：  
  • Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 286 and 529 of FGR.
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • FLJ43153 antibody; MGC75096 antibody; SRC2 antibody; c-fgr antibody; c-src2 antibody; p55-Fgr antibody; p55c-fgr antibody; p58c-fgr antibody; FGR antibody; c-src-2 proto-oncogene antibody; tyrosine-protein kinase Fgr antibody; proto-oncogene c-Fgr antibod
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total FGR protein.
  • Applications：  
  • WB
  • Background：  
  • This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]



 
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