Product Datasheet  
Grp78 Antibody  
Catalog Number: 35394  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P11021;
    NCBI Gene#:3309
  • Form of Antibody：  
  • Rabbit IgG in 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 478 and 654 of Grp78.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • BIP antibody; FLJ26106 antibody; GRP78 antibody; MIF2 antibody; HSPA5 antibody; immunoglobulin heavy chain-binding protein antibody; 78 kDa glucose-regulated protein antibody; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 antibody; "heat shoc
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total Grp78 protein.
  • Applications：  
  • WB
  • Background：  
  • When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]



 
© Signalway Biotechnology All Rights Reserved.