Product Datasheet  
GATA1(Phospho-Ser142) Antibody  
Catalog Number: 11041  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15976
    NCBI Protein: NP_002040.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine 142 (R-L-S(p)-P-D) derived from Human GATA1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 43kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:200

  • other_names：  
  • GAT1; GATA1; GF-1; NF-E1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Specificity：  
  • The antibody detects endogenous level of GATA1 only when phosphorylated at serine 142.
  • Applications：  
  • WB IHC IF
  • Background：  

  • GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

    Zon LI, et al. (1990) Proc Natl Acad. Sci USA. 87: 668-672.
    Trainor C D, et al. (1990) Nature. 343: 92-96.
    Nichols K E, et al. (2000) Nat Genet. 24: 266-270.




 
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