Product Datasheet  
ATP6V1E1 Antibody  
Catalog Number: 35378  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P36543;
    NCBI Gene#:529
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 1 and 226 of ATP6V1E1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • ATP6E antibody; ATP6E2 antibody; ATP6V1E antibody; P31 antibody; Vma4 antibody; ATP6V1E1 antibody; "H(+)-transporting two-sector ATPase; 31kDa subunit antibody"; "H+-transporting ATP synthase chain E; vacuolar antibody"; vacuolar proton pump subunit E 1 a
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total ATP6V1E1 protein.
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. [provided by RefSeq]



 
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