Product Datasheet
UAP56 Antibody
Catalog Number: 35371
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13838;
NCBI Gene#:7919
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 216 and 422 of UAP56.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- BAT1 antibody; D6S81E antibody; UAP56 antibody; DDX39B antibody; nuclear RNA helicase (DEAD family) antibody; 56 kDa U2AF65-associated protein antibody; ATP-dependent RNA helicase p47 antibody; spliceosome RNA helicase DDX39B antibody; HLA-B-associated tr
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total UAP56 protein.
- Background:
- This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
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