Product Datasheet  
CCR5 Antibody  
Catalog Number: 35367  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P51681;
    NCBI Gene#:1234
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein of human MSH2
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500-1:1000

  • other_names：  
  • CC-CKR-5 antibody; CCCKR5 antibody; CD195 antibody; CKR-5 antibody; CKR5 antibody; CMKBR5 antibody; FLJ78003 antibody; IDDM22 antibody; CCR5 antibody; C-C motif chemokine receptor 5 A159A antibody; HIV-1 fusion coreceptor antibody; C-C CKR-5 antibody; che
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total CCR5 protein.
  • Applications：  
  • WB
  • Background：  

  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]




 
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