Product Datasheet  
NQO1 Antibody  
Catalog Number: 35365  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P15559;
    NCBI Gene#:1728
  • Form of Antibody：  
  • Rabbit IgG in 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 1 and 274 of NQO1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • DHQU antibody; DIA4 antibody; DTD antibody; NMOR1 antibody; NMORI antibody; QR1 antibody; NQO1 antibody; phylloquinone reductase antibody; dioxin-inducible 1 antibody; azoreductase antibody; NAD(P)H:Quinone acceptor oxidoreductase type 1 antibody; quinone
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total NQO1 protein.
  • Applications：  
  • WB
  • Background：  
  • This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]



 
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