Product Datasheet  
CDK2 Antibody  
Catalog Number: 35361  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P24941;
    NCBI Gene#:1017
  • Form of Antibody：  
  • Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 1 and 269 of CDK2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:1000-1:10000
  • other_names：  
  • p33(CDK2) antibody; CDK2 antibody; cdc2-related protein kinase antibody; cell devision kinase 2 antibody; cyclin-dependent kinase 2 antibody; p33 protein kinase antibody; cell division protein kinase 2 antibody
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total CDK2 protein.
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]



 
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