Product Datasheet
Prothrombin Antibody
Catalog Number: 35360
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P00734;
NCBI Gene#:2147
- Form of Antibody:
- Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment contain a sequence corresponding to a region within amino acids 9 and 226 of Prothrombin.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- PT antibody; F2 antibody; prothrombin antibody; serine protease antibody; prothrombin B-chain antibody; coagulation factor II (thrombin) antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total Prothrombin protein.
- Background:
- Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq]
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