Product Datasheet  
Cytochrome C Antibody  
Catalog Number: 21680  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P99999
    Gene ID:54205
  • Form of Antibody：  
  • Storage：  
  • Immunogen：  
  • Peptide sequence around aa.71-75(N-P-K-K-Y) derived from Human Cytochrome C.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 14kd
    Western blotting: 1: 500~1: 1000
  • other_names：  
  • CYC, HCS, THC4,
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total Cytochrome C protein.
  • Applications：  
  • WB
  • Background：  
  • Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.



 
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