Product Datasheet  
Oct4 Antibody  
Catalog Number: 35351  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q01860;
    NCBI Gene#:5460
  • Form of Antibody：  
  • Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fragment corresponding to a region within amino acids 101 and 325 of OCT3/4.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:500-1:3000

  • other_names：  
  • MGC22487 antibody; OTF-3 antibody; OTF3 antibody; OTF4 antibody; POU5F1 antibody; POU-type homeodomain-containing DNA-binding protein antibody; octamer-binding protein 3 antibody; POU domain transcription factor OCT4 antibody; octamer-binding protein 4 an
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total Oct4 protein.
  • Applications：  
  • WB
  • Background：  

  • This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]




 
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