Product Datasheet
CD4 Antibody
Catalog Number: 35348
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P01730;
NCBI Gene#:920
- Form of Antibody:
- Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 172 and 414 of CD4.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- CD4mut antibody; CD4 antibody; CD4 receptor antibody; CD4 antigen (p55) antibody; T-cell surface glycoprotein CD4 antibody; T-cell surface antigen T4/Leu-3 antibody; CD4 molecule antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total CD4 protein.
- Background:
- This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq]
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