Product Datasheet
BCL2 Antibody
Catalog Number: 35342
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P10415;
NCBI Gene#:596
- Form of Antibody:
- Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Recombinant fragment corresponding to a region within amino acids 1 and 125 of BCL2.
- appl_detail:
- Western blotting: 1:1000-1:10000
- other_names:
- Bcl-2 antibody; BCL2 antibody; "protein phosphatase 1; regulatory subunit 50 antibody"; apoptosis regulator Bcl-2 antibody; B-cell CLL/lymphoma 2 antibody
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total BCL2 protein.
- Background:
- This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq]
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