Product Datasheet
CysLT1 Receptor Antibody
Catalog Number: 35340
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y271;
NCBI Gene#:10800
- Form of Antibody:
- Rabbit IgG in 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Immunogen:
- Synthetic peptide corresponding to a region within amino acids 203 and 296 of CysLT 1 Receptor.
- appl_detail:
- Western blotting: 1:500-1:3000
- other_names:
- CYSLT1 antibody; CYSLT1R antibody; CYSLTR antibody; HG55 antibody; HMTMF81 antibody; MGC46139 antibody; CYSLTR1 antibody; cysteinyl leukotriene receptor 1 antibody; cysteinyl leukotriene D4 receptor antibody; LTD4 receptor antibody; G-protein coupled rece
- Purification:
- Antibodies were purified by antigen-affinity chromatography.
- Specificity:
- The antibody detects endogenous levels of total CysLT1 Receptor protein.
- Background:
- The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq]
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