Product Datasheet  
Calcium Sensing Receptor Antibody  
Catalog Number: 35338  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P41180;
    NCBI Gene#:846
  • Form of Antibody：  
  • Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region within amino acids 402 and 496 of Calcium sensing Receptor.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:3000
  • other_names：  
  • CAR antibody; EIG8 antibody; FHH antibody; FIH antibody; GPRC2A antibody; HHC antibody; HHC1 antibody; MGC138441 antibody; NSHPT antibody; PCAR1 antibody; CASR antibody; parathyroid cell calcium-sensing receptor antibody; parathyroid Ca(2+)-sensing recept
  • Purification：  
  • Antibodies were purified by antigen-affinity chromatography.
  • Specificity：  
  • The antibody detects endogenous levels of total Calcium Sensing Receptor protein.
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq]



 
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