Product Datasheet
FCGR2A Antibody
Catalog Number: 35305
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P12318
NCBI Gene ID: 2212
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human FCGR2A.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total FCGR2A protein.
- Background:
- Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Stuart S.G., J. Exp. Med. 166:1668-1684(1987).
Brooks D.G., J. Exp. Med. 170:1369-1385(1989).
Gregory S.G., Nature 441:315-321(2006).
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