Product Datasheet
MATK Antibody
Catalog Number: 35281
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P42679
NCBI Gene ID: 4145
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human MATK.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CHK; Csk-homologous kinase; Csk-type protein tyrosine kinase; CTK; DKFZp434N1212
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MATK protein.
- Background:
- Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Sakano S., Oncogene 9:1155-1161(1994).
Bennett B.D., J. Biol. Chem. 269:1068-1074(1994).
Avraham S., J. Biol. Chem. 270:1833-1842(1995).
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