Product Datasheet  
BAG3 Antibody  
Catalog Number: 35276  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O95817
    NCBI Gene ID: 9531
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human BAG3.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • BAG-3; BAG-family molecular chaperone regulator-3; BCL-2 binding athanogene- 3; Bcl-2-binding protein Bis; BIS
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total BAG3 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.

    Takayama S., J. Biol. Chem. 274:781-786(1999).
    Lee J.H., Oncogene 18:6183-6190(1999).
    Doong H., Oncogene 19:4385-4395(2000).



 
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