Product Datasheet
CYP21A2 Antibody
Catalog Number: 35263
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P08686
NCBI Gene ID: 1589
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human CYP21A2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 21-hydroxylase; 21-OHase; CA21H; CAH1; CP21A
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CYP21A2 protein.
- Background:
- Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
Higashi Y., Proc. Natl. Acad. Sci. U.S.A. 83:2841-2845(1986).
White P.C., Proc. Natl. Acad. Sci. U.S.A. 83:5111-5115(1986).
Rodrigues N.R., EMBO J. 6:1653-1661(1987).
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