Product Datasheet
NRF1 Antibody
Catalog Number: 35250
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q16656
NCBI Gene ID: 4899
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human NRF1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal; NRF1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total NRF1 protein.
- Background:
- Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Virbasius C.A., Genes Dev. 7:2431-2445(1993).
Efiok B.J.S., J. Biol. Chem. 269:18921-18930(1994).
Gopalakrishnan L., J. Biol. Chem. 270:18019-18025(1995).
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