Product Datasheet
IL4 Antibody
Catalog Number: 35227
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P05112
NCBI Gene ID: 3565
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human IL4.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- B cell growth factor 1; B cell stimulatory factor 1; B-cell stimulatory factor 1; BCGF-1; BCGF1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total IL4 protein.
- Background:
- Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Yokota T., Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986).
Arai N., J. Immunol. 142:274-282(1989).
Klein S.C., Immunogenetics 41:57-57(1995).
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