Product Datasheet
IL15RA Antibody
Catalog Number: 35222
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q13261
NCBI Gene ID: 3601
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human IL15RA.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Interleukin-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; IL15RA;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total IL15RA protein.
- Background:
- High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK.
Anderson D.M., J. Biol. Chem. 270:29862-29869(1995).
Yu W., Genome Res. 7:353-358(1997).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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