Product Datasheet
FGF13 Antibody
Catalog Number: 35216
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q92913
NCBI Gene ID: 2258
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human FGF13.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total FGF13 protein.
- Background:
- Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. May regulate voltage-gated sodium channels transport and function. May also play a role in MAPK signaling.
Smallwood P.M., Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996).
Gecz J., Hum. Genet. 104:56-63(1999).
Ross M.T., Nature 434:325-337(2005).
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