Product Datasheet  
SIRT3 Antibody  
Catalog Number: 35202  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9NTG7
    NCBI Gene ID: 23410
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human SIRT3.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • NAD-dependent deacetylase sirtuin-3; mitochondrial; SIR2-like protein 3; hSIRT3; SIRT3
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SIRT3 protein.
  • Applications：  
  • WB
  • Background：  
  • NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

    Bechtel S., BMC Genomics 8:399-399(2007).
    Schwer B., J. Cell Biol. 158:647-657(2002).
    Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).



 
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