Product Datasheet  
CREB3L2 Antibody  
Catalog Number: 35185  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q70SY1
    NCBI Gene ID: 64764
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CREB3L2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • cAMP-responsive element-binding protein 3-like protein 2; BBF2 human homolog on chromosome 7; Processed cAMP-responsive element-binding protein 3-like protein 2; CREB3L2; BBF2H7
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CREB3L2 protein.
  • Applications：  
  • WB
  • Background：  
  • Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage By similarity.

    Storlazzi C.T., Hum. Mol. Genet. 12:2349-2358(2003).
    Ota T., Nat. Genet. 36:40-45(2004).
    Scherer S.W., Science 300:767-772(2003).



 
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