Product Datasheet
ZP1 Antibody
Catalog Number: 35166
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P60852
NCBI Gene ID: 22917
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ZP1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- mgc87693; zona pellucida glycoprotein 1; zona pellucida glycoprotein 1 (sperm receptor); zp1; zp1 protein
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ZP1 protein.
- Background:
- The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.
Hughes D.C., Biochim. Biophys. Acta 1447:303-306(1999).
Taylor T.D., Nature 440:497-500(2006).
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