Product Datasheet  
ZC3H8 Antibody  
Catalog Number: 35154  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q8N5P1
    NCBI Gene ID: 84524
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human ZC3H8.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Zinc finger CCCH domain-containing protein 8; ZC3H8; ZC3HDC8;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ZC3H8 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

    Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Hwang E.S., Immunology 106:464-469(2002).



 
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