Product Datasheet
ATP6V1H Antibody
Catalog Number: 35138
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UI12
NCBI Gene ID: 51606
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ATP6V1H.
- appl_detail:
Immunohistochemistry: 1:50~1:100
- other_names:
- Vacuolar proton pump subunit H; EC 3.6.3.14; V-ATPase subunit H; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit SFD
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ATP6V1H protein.
- Background:
- Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system By similarity. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.
Liu B., Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Lu X., Immunity 8:647-656(1998).
Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Lai C.-H., Genome Res. 10:703-713(2000).
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