Product Datasheet
USP11 Antibody
Catalog Number: 35115
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P51784
NCBI Gene ID: 8237
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human USP11.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Deubiquitinating enzyme 11; Ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase; X-linked; ubiquitin specific peptidase 11
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total USP11 protein.
- Background:
- Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
Ross M.T., Nature 434:325-337(2005).
Ideguchi H., Biochem. J. 367:87-95(2002).
Swanson D.A., Hum. Mol. Genet. 5:533-538(1996).
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