Product Datasheet
GTF3A Antibody
Catalog Number: 35104
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q92664
NCBI Gene ID: 2971
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human GTF3A.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- AP2; general transcription factor IIIA; GTF3A; TF3A; TFIIIA
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total GTF3A protein.
- Background:
- Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes.
Arakawa H., Cytogenet. Cell Genet. 70:235-238(1995).
Dunham A., Nature 428:522-528(2004).
Drew P.D., Gene 159:215-218(1995).
© Signalway Biotechnology All Rights Reserved.