Product Datasheet
SLCO1A2 Antibody
Catalog Number: 35067
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P46721
NCBI Gene ID: 6579
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human SLCO1A2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- OATP; OATP-A; OATP1; OATP1A2; organic anion transporting polypeptide A
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SLCO1A2 protein.
- Background:
- Mediates the Na+-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids By similarity. Selectively inhibited by the grapefruit juice component naringin.
Kullak-Ublick G.-A., Gastroenterology 109:1274-1282(1995).
Koenig J., J. Biol. Chem. 275:23161-23168(2000).
Lee W., J. Biol. Chem. 280:9610-9617(2005).
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