Product Datasheet
SCN4B Antibody
Catalog Number: 35053
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P16949
NCBI Gene ID: 6330
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human SCN4B.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Sodium channel subunit beta-4 [Precursor]; SCN4B;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SCN4B protein.
- Background:
- Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear By similarity.
Yu F.H., J. Neurosci. 23:7577-7585(2003).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Medeiros-Domingo A., Circulation 116:134-142(2007).
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