Product Datasheet  
SHC3 Antibody  
Catalog Number: 35048  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P16949
    NCBI Gene ID: 53358
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human SHC3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • SHC-transforming protein 3; SH2 domain protein C3; Src homology 2 domain-containing-transforming protein C3; Neuronal Shc; N-Shc
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SHC3 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear By similarity.

    Nakamura T., Oncogene 13:1111-1121(1996).
    Pelicci G., Oncogene 13:633-641(1996).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).



 
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