Product Datasheet
RHG9 Antibody
Catalog Number: 34989
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9BRR9
NCBI Gene ID: 64333
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human RHG9.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- RGL1; RHG09; rho GTPase activating 9;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total RHG9 protein.
- Background:
- GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Furukawa Y., Biochem. Biophys. Res. Commun. 284:643-649(2001).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Kawasoe T., Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
© Signalway Biotechnology All Rights Reserved.