Product Datasheet
RGS12 Antibody
Catalog Number: 34981
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O14924
NCBI Gene ID: 6002
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human RGS12.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- regulator of G-protein signaling 12;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total RGS12 protein.
- Background:
- Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. soform 5:Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.
Chatterjee T.K., J. Biol. Chem. 275:29660-29671(2000).
Snow B.E., J. Biol. Chem. 273:17749-17755(1998).
Hillier L.W., Nature 434:724-731(2005).
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