Product Datasheet
PTRF Antibody
Catalog Number: 35182
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q6NZI2
NCBI Gene ID: 284119
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human PTRF.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CAVIN; Cavin-1; CGL4; FKSG13; FLJ90031
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PTRF protein.
- Background:
- Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.
Wang Y.-G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Jansa P., EMBO J. 17:2855-2864(1998).
Aboulaich N., Biochem. J. 383:237-248(2004).
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