Product Datasheet  
CHML Antibody  
Catalog Number: 34948  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P26374
    NCBI Gene ID: 1122
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CHML.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Rab proteins geranylgeranyltransferase component A 2; Rab escort protein 2; REP-2; Choroideraemia-like protein;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CHML protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

    Cremers F.P.M., Hum. Mol. Genet. 1:71-75(1992).
    Kasper G., Gene 295:27-32(2002).
    Ota T. Nat. Genet. 36:40-45(2004)



 
© Signalway Biotechnology All Rights Reserved.