Product Datasheet
PPM1L Antibody
Catalog Number: 34934
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q5SGD2
NCBI Gene ID: 151742
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human PPM1L.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- mgc132545; mgc132547; pp2c-epsilon; pp2ce; ppm1-like
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PPM1L protein.
- Background:
- Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
Jin F., Mol. Biol. Rep. 31:197-202(2004).
Ota T., Nat. Genet. 36:40-45(2004).
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