Product Datasheet
NDRG4 Antibody
Catalog Number: 34930
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9ULP0
NCBI Gene ID: 65009
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human NDRG4.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- Brain development-related molecule 1; Protein NDRG4; SMAP-8; Vascular smooth muscle cell-associated protein 8;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total NDRG4 protein.
- Background:
- Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress By similarity. May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
Zhou R.-H., Genomics 73:86-97(2001).
Nishimoto S., Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Qu X., Mol. Cell. Biochem. 229:35-44(2002).
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