Product Datasheet
PEBP1 Antibody
Catalog Number: 34900
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P30086
NCBI Gene ID: 5037
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human PEBP1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 23 kDa morphine-binding protein; B-RAF proto-oncogene serine/threonine-protein kinase; HCNP; Hippocampal cholinergic neurostimulating peptide; Neuropolypeptide h3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total PEBP1 protein.
- Background:
- Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor By similarity.
Hori N., Gene 140:293-294(1994).
Tohdoh N., Brain Res. Mol. Brain Res. 30:381-384(1995).
Hochstrasser D.F., Electrophoresis 13:992-1001(1992).
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