Product Datasheet
EHHADH Antibody
Catalog Number: 34890
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q08426
NCBI Gene ID: 1962
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human EHHADH.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- EC 1.1.1.35; EC 4.2.1.17; EC 5.3.3.8; ECHD; ECHP
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total EHHADH protein.
- Background:
- The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Hoefler G., Genomics 19:60-67(1994).
Cherkaoui-Malki M., Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
Totoki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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