Product Datasheet
NARFL Antibody
Catalog Number: 34870
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9H6Q4
NCBI Gene ID: 64428
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human NARFL.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- FLJ21988; Nuclear prelamin A recognition factor- like; PRN; Protein related to Narf;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total NARFL protein
- Background:
- Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
Wang M., Proc. Natl. Acad. Sci. U.S.A. 91:10591-10595(1994).
Van Eynde A., Eur. J. Biochem. 261:291-300(1999).
Liu J.P., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
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