Product Datasheet  
ME1 Antibody  
Catalog Number: 34842  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P48163
    NCBI Gene ID: 4199
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human ME1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • NADP-dependent malic enzyme; EC 1.1.1.40; NADP-ME; Malic enzyme 1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ME1 protein.
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

    Loeber G., FEBS Lett. 344:181-186(1994).
    Gonzalez-Manchon C., Gene 159:255-260(1995).
    Totoki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.




 
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