Product Datasheet  
NDUFS1 Antibody  
Catalog Number: 34838  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: P28331
    NCBI Gene ID: 4719
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthesized peptide derived from C-terminal of human NDUFS1.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names:  
  • NADH-ubiquinone oxidoreductase 75 kDa subunit; mitochondrial; Complex I-75kD; CI-75kD;
  • Purification:  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity:  
  • The antibody detects endogenous levels of total NDUFS1 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.

    Chow W., Eur. J. Biochem. 201:547-550(1991).
    Hillier L.W., Nature 434:724-731(2005).



 
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