Product Datasheet
SLC9A3R2 Antibody
Catalog Number: 34825
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q15599
NCBI Gene ID: 9351
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human SLC9A3R2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHERF-2; NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SLC9A3R2 protein.
- Background:
- Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.
Poulat F., J. Biol. Chem. 272:7167-7172(1997) [PubMed: 9054412].
Reczek D.,J. Cell Biol. 139:169-179(1997) [PubMed: 9314537].
Yun C.H.C., Proc. Natl. Acad. Sci. U.S.A. 94:3010-3015(1997) [PubMed: 9096337].
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